Complex Regional Pain Syndrome

Complex Regional Pain Syndrome (CRPS) is a chronic pain condition resulting from dysfunction in the central or peripheral nervous system. It is characterised by severe and persistent neuropathic pain that is disproportionate to the initial injury.

 

Symptoms:

– Severe, burning, or throbbing pain.

– Increased sensitivity to touch or cold (allodynia) in the affected area.

– The skin over the affected region may appear shiny, thin, or dry.

– The affected limb may feel warmer or cooler than the unaffected one.

– Altered skin colour: red, blue, or blotchy in the affected area.

– Persistent swelling in the affected region.

– Stiffness and reduced range of motion in the involved joints.

– Muscle weakness or atrophy in the affected limb.

– Increased or decreased hair and nail growth on the affected limb.

– Difficulty using the affected limb due to pain or weakness.

 

Causes:

The precise cause of CRPS remains unclear, but it may involve:

– Abnormal nerve signalling

– Immune system response causing inflammation

– Injuries: sprains, fractures, surgery, or minor injuries can trigger CRPS.

 

Assessment and Diagnosis:

To effectively understand and treat CRPS, a thorough evaluation is essential for identifying the underlying cause. This includes the following components:

  • A comprehensive history and assessment are vital
  • Investigations: MRI, X-ray, CT scan, Bone scans
  • Sympathetic nerve blocks: for diagnosis
  • Follow-up for a personalised multimodal management plan
  • Review of the agreed-tailored pathway outcomes

Multimodal Treatment:

The cornerstone of the treatment is the management of symptoms and the functional restoration of the affected area. It includes the following:

– Initiating oral analgesics, such as anti-neuropathic medication

– Topical treatments: Lidocaine or Capsaicin patches for localised neuropathic pain

– Physiotherapy for the functional restoration of joints

– Sympathetic nerve blocks (Lumbar, Stellate ganglion)

– Psychological support: stress management, cognitive behavioural therapy (CBT)

– Spinal cord stimulation: an implanted device for modulating pain signals